Superstars and fantasy game-changers being injured is always going to be part of the fantasy football game that gives managers the most distress over the weekend. Let’s make your life easier by cutting to the brass tacks and outlining every relevant current injury designation and what it implies for the fantasy outlook for Week 10.
This series will continue to be live every Saturday morning, meaning that if brand new statuses appear later in the weekend, they are not covered here. You can also follow me on Twitter (@AhaanRungta) for more regular fantasy football discussions, including comments on injury-riddled fantasy rosters. If a game does not appear on this list, that means there is currently no current injury threat in the realm of fantasy relevance.
More fantasy football fun for Week 10: Waiver Wire | FAAB Guide | Start & Sit | Loves & Hates | Stock Watch | Sleepers & Streamers | D/ST Streamers
Week 10 NFL Inactives
New Orleans Saints vs. Tennessee Titans
QUESTIONABLE: WR Julio Jones, TEN (hamstring)
OUT: RB Alvin Kamara, NO (knee)
As if there wasn’t already enough significant star power missing from both teams… With starting quarterback Jameis Winston and wide receiver Michael Thomas already ruled out for the season, superstar running back Alvin Kamara joined the list. After not practicing at all this week, Kamara is in no shape to participate in Week 10. In his absence, Mark Ingram will lead the Saints backfield with Dwayne Washington serving backup duties and wide receiver Ty Montgomery also having experience at running back, although Montgomery is questionable as well.
For the Titans, MVP candidate Derrick Henry is already out for an extended period of time. After some quick scares to the availability of A.J. Brown and Ryan Tannehill after Friday practice, it was revealed that Tannehill was ill and Brown was just not in a state to participate fully. However, both are expected to be active for this Week 10 matchup as they are now off the injury report. The non-survivor from the injury train is, again, Julio Jones. After already missing three full games this season, Jones is questionable with a hamstring injury and could be a gametime decision on Sunday.
Buffalo Bills vs. New York Jets
QUESTIONABLE: RB Zack Moss, BUF (concussion)
QUESTIONABLE: WR Corey Davis, NYJ (hip)
DOUBTFUL: QB Zach Wilson, NYJ (knee)
After injuring his hip in Week 7, rookie quarterback Zach Wilson was replaced by Mike White, who put up a legendary 400-yard passing game in Week 8, after which some questions arose about the safety of the quarterback situation for the Jets. Fast-forward two weeks and more injuries and Wilson was back in practice with full participation and is currently doubtful for a Week 10 matchup against the tough Buffalo Bills, who might be playing with more urgency after losing a stunner to the Jacksonville Jaguars in Week 9.
Regardless of who starts at quarterback for the Jets, you are not likely starting the man under center. However, the Jets’ pass-catching unit might get a needed boost if wide receiver Corey Davis is able to return. Davis also has missed two weeks but, like Wilson, was a full participant in practice on Friday and is trending upwards to an active status for Week 10.
On the Buffalo Bills side, they have been fairly healthy for the fantasy scheme this season but emerging stud running back Zack Moss is in danger of missing out on an easy matchup in Week 10. After suffering a concussion early in the Bills’ Week 9 game, Moss is in the NFL’s concussion protocol but is trending upwards and could suit up on Sunday against the Jets. His status is simply one fantasy managers must keep an eye on over the weekend. If he is playing, it is difficult to justify sitting him with his ability to produce in the red zone against a team that will likely allow the Bills to have their way on offense.
Detroit Lions vs. Pittsburgh Steelers
OUT: RB Jamaal Williams, DET (thigh)
OUT: WR Chase Claypool, PIT (toe)
The Lions have already had some issues with health on the offensive end of the ball, with second-year wide receiver Quintez Cephus on the injured reserve and wide receiver Tyrell Williams waived with an injury settlement. This week, it’ll be backup running back Jamaal Williams missing his second straight game due to a thigh issue.
In Williams’ absence in Week 8 before the Lions’ Week 9 bye, D’Andre Swift unsurprisingly took on the lion’s share of the running back workload. Backups Jermar Jefferson and Godwin Igwebuike also received some opportunities, but primarily after they were getting blown out by the Eagles. Neither Jefferson nor Igwebuike should be considered fantasy-relevant. Meanwhile, Swift remains an auto-start in all formats.
For the Steelers, JuJu Smith-Schuster was already ruled out for the remainder of the system and their wide receiver room is just getting worse with the second-year wideout Chase Claypool ruled out for a Week 10 matchup against an incompetent Lions secondary. Luckily, Claypool seems to have avoided an injury of the season-ending variety. In his absence, Diontae Johnson should be a candidate to be one of the biggest target hogs in the NFL while James Washington will likely serve as the Steelers’ WR2.
Jacksonville Jaguars vs. Indianapolis Colts
QUESTIONABLE: RB James Robinson, JAX (heel)
The Jaguars stunned the Bills in Week 9 to win a low-scoring affair. They did so without their starting running back James Robinson, who was injured early in the Jaguars’ Week 8 game in Seattle. Robinson is trending upwards with this heel injury as he participated in limited fashion in practice on Friday. He will be a gametime decision on Sunday against a Colts defense that ranks #2 in the NFL in rush DVOA. If Robinson is unable to suit up, Carlos Hyde would start at running back and be backed up by Dare Ogunbowale and Devine Ozigbo.
Meanwhile, the Colts do not have any developing offensive injuries that should affect the fantasy game heavily. Their offensive line is trending in the right direction and continues to be one of the many reasons Jonathan Taylor is a top 2 running back in fantasy football.
Tampa Bay Buccaneers vs. Washington Football Team
QUESTIONABLE: WR Chris Godwin, TB (foot)
OUT: WR Antonio Brown, TB (ankle) / TE Rob Gronkowski, TB (back)
I thought I caught a break not having to type out injury reports for the Ravens (Thursday Night Football) and the Giants (bye). But the Buccaneers are challenging that level of misfortune with injuries to their roster. The ones that are relevant to their fantasy roster are game-changers for the landscape of pass-catchers. With Antonio Brown and Rob Gronkowski already ruled out, wide receiver Tyler Johnson becomes an immediate FLEX candidate in all leagues. To make matters even more dicey, Chris Godwin is no lock to suit up. Godwin did practice on Friday but Tampa Bay head coach Bruce Arians suggested a final decision will have to be made over the weekend after further evaluation.
Weekly reminder that Tyler Johnson has to be rostered in #FantasyFootball. 5-6-65 in Week 8 with Brown out and Gronkowski essentially out. WAS doesn't guard WR.
I'm likely starting him in the FLEX in a 0.5-PPR league in Week 10 as well. https://t.co/MlmbYn9DF7
— Ahaan Rungta (@AhaanRungta) November 12, 2021
Washington has no new developments in the fantasy-relevant injury scene; wide receiver Curtis Samuel and tight end Logan Thomas remain out and will be candidates to return next Week 11.
Cleveland Browns vs. New England Patriots
QUESTIONABLE: RB Damien Harris, NE (concussion) / RB Rhamondre Stevenson, NE (concussion)
OUT: RB Nick Chubb, CLE (COVID-19) / RB Demetric Felton, CLE (COVID-19)
Running back madness for both teams here—three running backs for the Browns tested positive for COVID-19 and have been ruled out for this competitive Week 10 matchup. In their place, D’Ernest Johnson will take on the lead role for the Browns backfield.
For the Patriots, starter Damien Harris and third-stringer Rhamondre Stevenson are both dealing with concussions that keep their status uncertain for Week 10. The other running backs on the New England depth chart are Brandon Bolden, followed by J.J. Taylor.
Atlanta Falcons vs. Dallas Cowboys
QUESTIONABLE: WR Cedrick Wilson, DAL (shoulder)
OUT: TE Blake Jarwin, DAL (hip)
The Cowboys’ top two wide receivers have been dealing with some recent injuries but neither Amari Cooper nor CeeDee Lamb are listed on the injury report. Instead, the regular Dallas WR3 Michael Gallup remains on the injured reserve and unavailable to play and his replacement Cedrick Wilson is now questionable due to a shoulder injury that kept him limited in practice on Friday. Additionally, Blake Jarwin is on the injured reserve and unavailable till at least Week 12; in the meantime, Dalton Schultz should absorb the majority of the Cowboys’ snaps at tight end.
The Falcons have no moving parts on the injury report relevant to fantasy lineups headed into Week 10. Other than Calvin Ridley still being out due to a personal issue, the Falcons should send out the majority of their offense to compete in Week 10 against a Cowboys defense that has made plays but been inconsistent this season.
Carolina Panthers vs. Arizona Cardinals
QUESTIONABLE: QB Kyler Murray, ARI (ankle) / WR DeAndre Hopkins, ARI (hamstring) / WR Rondale Moore, ARI (concussion)
OUT: QB Sam Darnold, CAR (shoulder)
OUT: RB Chase Edmonds, ARI (ankle)
The Panthers now have multiple MVPs on their quarterback depth chart—former NFL MVP Cam Newton and their Week 10 starter, former XFL MVP P.J. Walker.
Breaking: The Panthers announced they have agreed to terms with QB Cam Newton.
He's back. pic.twitter.com/I9tcl4DySX
— SportsCenter (@SportsCenter) November 11, 2021
All of this was triggered by the concussion to Sam Darnold, who is expected to be on the injured reserve till at least Week 14.
For the Cardinals, most of their fantasy-relevant stars have dealt with something nagging their health recently. That continues entering Week 10 as quarterback Kyler Murray and wide receivers DeAndre Hopkins, and Rondale Moore are all trending towards being game-time decisions on Sunday. The Cardinals play at 4 PM ET, so fantasy managers should not just rely on hoping Murray, Hopkins, or Moore suit up. Have a contingency plan and make sure you do not drop Murray or Hopkins in any league or Moore in deep leagues. If Murray is out, Colt McCoy will make his second straight start for the Cardinals.
Additionally, Chase Edmonds is for sure out, leaving James Conner the task of leading the Cardinals backfield again. In Week 10, with Edmonds missing most of the game due to injury, Conner exploded for 173 scrimmage yards and 3 touchdowns. He has been a red zone monster and a touchdown machine this season and will be backed up by Eno Benjamin against the Panthers.
Minnesota Vikings vs. Los Angeles Chargers
QUESTIONABLE: WR Keenan Allen, LAC (knee)
DOUBTFUL: RB Justin Jackson, LAC (quadriceps)
There are very few fantasy-football-shaking injuries to report for this game, which is projected to be a close one filled with offensive potential. Vikings running back Dalvin Cook deals with issues off the field but his availability for NFL action is currently not in question.
#Vikings coach Mike Zimmer on Dalvin Cook's availability for Sunday: Said he hasn't heard anything. Asked if it's a distraction, he said, "Not really."
— Chris Tomasson (@christomasson) November 10, 2021
On the Chargers side, backup running back Justin Jackson is in danger of missing more time after not suiting up in Week 9. However, starting running back Austin Ekeler’s fantasy value is in an elite tier regardless of Jackson’s status. Veteran wide receiver Keenan Allen was limited in practice on Friday with a knee issue but is currently expected to suit up in Week 10.
Seattle Seahawks vs. Green Bay Packers
IN: QB Russell Wilson, SEA (finger)
OUT: RB Chris Carson, SEA (neck)
QUESTIONABLE: QB Aaron Rodgers, GB (COVID-19)
In just a matter of days, we can turn this game from Geno Smith vs. Jordan Love to… Russell Wilson vs. Aaron Rodgers. All we need for that to be the case is for Rodgers to be cleared from the COVID-19 protocol ahead of the game, which the Packers currently expect to be the case.
It’s Time. pic.twitter.com/DVdHxn9hos
— Russell Wilson (@DangeRussWilson) November 8, 2021
In addition to Wilson making the quick turnaround and returning for the Seahawks, the Seattle offense teased us with a possible Chris Carson return to lead the backfield. However, Carson’s neck injury is still significant enough for head coach Pete Carroll to classify playing him in Week 10 as a risk not worth taking. Carson’s return will have to wait at least one more week.
Philadelphia Eagles vs. Denver Broncos
IN: TE Noah Fant, DEN (COVID-19)
QUESTIONABLE: WR Tim Patrick, DEN (knee) / TE Albert Okwuegbunam, DEN (knee)
The Eagles are still dealing with a Miles Sanders stint on the injured reserve. In Sanders’ absence, Jordan Howard, Boston Scott, and Kenneth Gainwell are busy creating pure chaos for fantasy owners trying to read usages and production for backfield committees. Other than that situation, the Eagles have no immediate fantasy-relevant injury concerns.
The Broncos are beaten up all over their roster but among fantasy-relevant starters, talented wide receiver Tim Patrick and tight end Albert Okwuegbunam were both limited in practice on Thursday with knee issues and are listed as questionable for Week 10. Okwuegbunam, however, was a long shot to be fantasy-relevant anyway since starting tight end Noah Fant has been activated from the COVID-19 list and is good to go against the Eagles to support top wide receivers Courtland Sutton, Jerry Jeudy, and, if healthy, Tim Patrick.
Los Angeles Rams vs. San Francisco 49ers
QUESTIONABLE: WR Odell Beckham Jr., LAR (shoulder, team decision)
QUESTIONABLE: RB Elijah Mitchell, SF (ribs) / RB JaMycal Hasty, SF (ankle) / TE George Kittle, SF (calf)
For the Los Angeles Rams, things cannot be going much better. They are primarily healthy and none of their fantasy owners are dealing with injury designations. And they just signed a 3-time Pro-Bowler in wide receiver Odell Beckham Jr. While Beckham passed his physical and will travel with the Rams for this Monday Night Football matchup, it is unclear if he will play or not. He and the team still have time to figure that out as he signed on Thursday but did not practice on Friday.
Sean McVay on whether new Rams’ WR Odell Beckham Jr. will play Monday night at San Francisco: “We’ll see. We're going to take it a day at a time. But if we feel like he can help us go compete against the 49ers, then we'll have him ready to go.”
— Adam Schefter (@AdamSchefter) November 13, 2021
The 49ers don’t have it quite as swimmingly in the health department. At practice on Friday, running back JaMycal Hasty was absent and running back Elijah Mitchell was limited. The 49ers also roster a healthy Jeff Wilson Jr. and Trenton Cannon at running back. Additionally, star tight end George Kittle made his return to the San Francisco lineup in Week 9 but was limited in practice on Friday. Kittle’s status will have to be monitored over the weekend. If he is in danger of missing the Monday Night Football contest, fantasy managers need to have a backup plan at tight end.
Week 10 Rankings: QB | RB | WR | TE | Kicker | D/ST | PPR | Flex
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